A Novel Way to
Measure Biology
3–D Sequencing™ combines high-speed 3D imaging with molecular sequencing to generate unique biological data at unprecedented scale.

SYSTEM
THETA
™
Theta is the world’s first 3D sequencing system.
• 3000× faster unstitched 3D imaging, generating 7.7T voxels
• Read sequence directly inside cells (In Situ Sequencing)
• Subcellular resolution in 3D: 250nm (xy) / 650 nm (z)
• Up to 20M suspended cells per run
• Compatible with cells, tissues, and DNA libraries
One System
Three Innovations
Three proprietary innovations work together to deliver the scale, biological context and molecular ground truth biological AI needs.

3D Matrix
Embeds biological samples in a three-dimensional volume, preserving spatial context while enabling sequencing in situ.

3D Fluidics
Moves sequencing reagents rapidly through the Matrix, enabling repeated chemistry cycles at scale.

3D Imaging
Powered by the world’s fastest confocal imaging system, capturing large biological volumes in 3D at subcellular resolution.
data production site
From Technology
to Biological Data
Our Data Production Site turns 3D sequencing into rich, scalable biological datasets, combining molecular information with preserved biological structure to power research and AI.


